Edited Transcript of AMC.AX earnings conference call or presentation 7-Nov-19 10:30pm GMT

Abbotsford, Victoria Nov 12, 2019 (Thomson StreetEvents) — Edited Transcript of Amcor Pty Ltd earnings conference call or presentation Thursday, November 7, 2019 at 10:30:00pm GMT UBS Investment Bank, Research Division – Executive Director & Research Analyst of Industrial Materials Ladies and gentlemen, thank you for standing by, and welcome to the Amcor First Quarter 2020 Results Conference Call. (Operator Instructions) I would now like to hand the conference over to your speaker today, Tracey Whitehead. Please go ahead. Thank you, and welcome to Amcor’s 2020 First Quarter Earnings Call. Good evening to those of you in the U.S., and good morning to those in Australia. Joining me on the call today is Ron Delia, Chief Executive Officer; and Michael Casamento, Chief Financial Officer. At this time, I’ll direct you to our website, amcor.com under the Investors section, where you’ll find our press release and presentation which will be discussed on this call. We’ll also discuss non-GAAP financial measures as we talk about performance against combined comparative information. Reconciliations of these non-GAAP measures can be found on the press...

Conjugated polymers optically regulate the fate of endothelial colony-forming cells

↵‡ Present address: Dipartimento di Ingegneria Meccanica e Aerospaziale, Politecnico di Torino, Corso Duca degli Abruzzi 24, 10129 Torino, Italy. ↵§ Present address: Smart Bio-Interfaces Italian Institute of Technology, Viale Rinaldo Piaggio 34, 56025 Pontedera (PI), Italy. The control of stem and progenitor cell fate is emerging as a compelling urgency for regenerative medicine. Here, we propose a innovative strategy to gain optical control of endothelial colony-forming cell fate, which represents the only known truly endothelial precursor showing robust in vitro proliferation and overwhelming vessel formation in vivo. We combine conjugated polymers, used as photo-actuators, with the advantages offered by optical stimulation over current electromechanical and chemical stimulation approaches. Light modulation provides unprecedented spatial and temporal resolution, permitting at the same time lower invasiveness and higher selectivity. We demonstrate that polymer-mediated optical excitation induces a robust enhancement of proliferation and lumen formation in vitro. We identify the underlying biophysical pathway as due to light-induced activation of TRPV1 channel. Altogether, our r...